Off the coast of the volcanic island of Santorini, the intrepid archaeologist, Lara Croft, makes the unexpected discovery of a throbbing golden orb able to guide its holder to the mythical Pandora's Box. As the legendary artefact contains ancient mysteries of unfathomable power, Lara needs to make sure it doesn't fall into the wrong hands, especially the unscrupulous former Nobel Prize winner and now a bio-weapons dealer, Jonathan Reiss.